Immune cell profiling in Gleason 9 prostate cancer patients treated with brachytherapy versus external beam radiotherapy: An exploratory study
نویسندگان
چکیده
This exploratory study evaluates immunological changes in high-risk Gleason 9 prostate cancer patients treated with EBRT+BT compared to EBRT alone. Notably, BT demonstrates the potential elicit a T cell response which may support further investigation using circulating immune cells as predictive and prognostic biomarkers for radiotherapy response.
منابع مشابه
Combining external beam radiotherapy with prostate brachytherapy: issues and rationale.
a he optimal treatment for clinically localized prostate cancer remains controversial. For paients with low-risk prostate cancer (Stage T1c2a, Gleason score less than 7, prostate-specific ntigen [PSA] of 10.0 ng/mL), monotherapy with adical prostatectomy, three-dimensional conforal radiotherapy (3D-CRT), intensity-modulated T, or prostate brachytherapy results in similar iochemical relapse-free...
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متن کاملExternal Beam Radiotherapy in Prostate Cancer
For the first time in their history, the 2 medical organizations most responsible for the treatment of prostate cancer in the United States—the American Society for Radiation Oncology (ASTRO) and the American Urological Association (AUA)—have issued a joint guideline, a series of 9 major statements on the use of radiation therapy (either adjuvant or salvage) after prostatectomy. The statements ...
متن کاملExternal Beam Radiotherapy in Prostate Cancer
For the first time in their history, the 2 medical organizations most responsible for the treatment of prostate cancer in the United States—the American Society for Radiation Oncology (ASTRO) and the American Urological Association (AUA)—have issued a joint guideline, a series of 9 major statements on the use of radiation therapy (either adjuvant or salvage) after prostatectomy. The statements ...
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ژورنال
عنوان ژورنال: Radiotherapy and Oncology
سال: 2021
ISSN: ['1879-0887', '0167-8140']
DOI: https://doi.org/10.1016/j.radonc.2020.10.029